A traumatic brain injury (TBI) is a serious medical issue that affects how your brain works. You can get a TBI from a hard bump or jolt to your head or if you're hit with something that penetrates your skull. Traumatic brain injuries are a major cause of death and disability in the world. They can cause short-term and long-term medical issues that can affect every part of your life.

If you have a traumatic brain injury, it means you were hit in the head hard enough to make your brain bounce around or twist inside your skull. When that happens, you can damage your brain and injure blood vessels in your brain. A TBI creates chemical changes in your brain so your brain cells don't function as they should.

Traumatic brain injury symptoms vary depending on whether a TBI is mild or moderate and/or severe. But all TBIs may cause symptoms, including physical issues, trouble thinking or remembering, and social or emotional issues. Children and adults have similar symptoms. TBI symptoms in babies are issues eating or nursing. They may cry inconsolably, meaning nothing you do to comfort them helps them stop crying.

Symptoms

Traumatic brain injury can have wide-ranging physical and psychological effects. Some signs or symptoms may appear immediately after the traumatic event, while others may appear days or weeks later.

Mild traumatic brain injury

The signs and symptoms of mild traumatic brain injury may include:

Physical symptoms

• Headache
• Nausea or vomiting
• Fatigue or drowsiness
• Problems with speech
• Dizziness or loss of balance

Sensory symptoms

• Sensory problems, such as blurred vision, ringing in the ears, a bad taste in the mouth or changes in the ability to smell
• Sensitivity to light or sound

Cognitive, behavioral or mental symptoms

• Loss of consciousness for a few seconds to a few minutes
• No loss of consciousness, but a state of being dazed, confused or disoriented
• Memory or concentration problems
• Mood changes or mood swings
• Feeling depressed or anxious
• Difficulty sleeping
• Sleeping more than usual

Moderate to severe traumatic brain injuries

Moderate to severe traumatic brain injuries can include any of the signs and symptoms of mild injury, as well as these symptoms that may appear within the first hours to days after a head injury:

Physical symptoms

• Loss of consciousness from several minutes to hours
• Persistent headache or headache that worsens
• Repeated vomiting or nausea
• Convulsions or seizures
• Dilation of one or both pupils of the eyes
• Clear fluids draining from the nose or ears
• Inability to awaken from sleep
• Weakness or numbness in fingers and toes
• Loss of coordination

Cognitive or mental symptoms

• Profound confusion
• Agitation, combativeness or other unusual behavior
• Slurred speech
• Coma and other disorders of consciousness

Stem Cells' Potential for Traumatic Brain Injuries

Traumatic Brain Injuries (TBIs), often resulting from severe head impacts, have garnered substantial media attention, particularly in sports like football, where such incidents are unfortunately frequent. These injuries can lead to enduring disruptions in normal brain function, manifesting as diminished cognition, impaired motor abilities, or, tragically, premature mortality.

Mesenchymal stem cells, inherently prolific in producing growth and trophic factors essential for neural development and maintenance, offer newfound hope for TBI patients. By infusing MSCs, damaged neurons can be rejuvenated, and the factors secreted by these cells play a pivotal role in facilitating neuronal regeneration.

Protocol

Intrathecal transplantation of cord tissue-derived Mesenchymal Stem Cells into the affected area. This minimally invasive procedure boasts a brief duration of approximately 45 minutes and is associated with minimal downtime. Patients typically return home just two days after their scheduled appointment.

Treatment Objectives

At the core of our protocol lies the overarching aim of substantially reducing chronic low-grade inflammation throughout the body. The enduring effects are anticipated to contribute to an extended period of improved well-being.

Stem cells exhibit an innate and unique ability to gravitate toward sites of damage and inflammation within the body. Research has illuminated their capacity to orchestrate the repair and regeneration of deteriorated tissues while fine-tuning the immune system, ultimately fostering enhanced health.

Depending on the specific ailment or the patient's initial condition, the benefits of stem cell therapy can encompass a notable reduction in distressing symptoms, a deceleration in disease progression, and an overall elevation in quality of life.